Posts belonging to Category 'Travaux scientifiques'
juin 13, 2017 | Posted by admin
Un nouvel article scientifique intitulé «Remission is related to CRP and smoking in early axial spondyloarthritis. The DESIR cohort.» a été publié dans le journal Ann Rheum Dis.
Molto A, Tezenas du Montcel S, Wendling D, Dougados M, Vanier A, Gossec L
Ann Rheum Dis. 2016 Nov 25. pii: annrheumdis-2016-209785.
Abstract
BACKGROUND:
Disease activity may change over time in axial [...]
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mai 19, 2017 | Posted by admin
Un nouvel article scientifique intitulé «Is the current ASAS expert definition of a positive family history useful in identifying axial spondyloarthritis? Results from the SPACE and DESIR cohorts.» a été publié dans le journal Arthritis Res Ther.
Ez-Zaitouni Z, Hilkens A, Gossec L, Berg IJ, Landewé R, Ramonda R, Dougados M, van der Heijde [...]
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février 17, 2017 | Posted by admin
Abstract
OBJECTIVES:
Investigating the utility of adding structural lesions seen on MRI of the sacroiliac joints to the imaging criterion of the Assessment of SpondyloArthritis (ASAS) axial SpondyloArthritis (axSpA) criteria and the utility of replacement of radiographic sacroiliitis by structural lesions on MRI.
METHODS:
Two well-calibrated readers scored MRI STIR (inflammation, MRI-SI), MRI T1-w images (structural lesions, MRI-SI-s) and radiographs of the sacroiliac joints (X-SI) of patients in the DEvenir des Spondyloarthrites Indifférenciées Récentes cohort (inflammatory back pain: ≥3 months, <3 years, age <50). A third reader adjudicated MRI-SI and X-SI discrepancies. Previously proposed cut-offs for a positive MRI-SI-s were used (based on <5% prevalence among no-SpA patients): erosions (E) ≥3, fatty lesions (FL) ≥3, E/FL ≥5. Patients were classified according to the ASAS axSpA criteria using the various definitions of MRI-SI-s.
RESULTS:
Of the 582 patients included in this analysis, 418 fulfilled the ASAS axSpA criteria, of which 127 patients were modified New York (mNY) positive and 134 and 75 were MRI-SI-s positive (E/FL≥5) for readers 1 and 2, respectively. Agreement between mNY and MRI-SI-s (E/FL≥5) was moderate (reader 1: κ: 0.39; reader 2: κ: 0.44). Using the E/FL≥5 cut-off instead of mNY classification did not change in 478 (82.1%) and 469 (80.6%) patients for readers 1 and 2, respectively. Twelve (reader 1) or ten (reader 2) patients would not be classified as axSpA if only MRI-SI-s was performed (in the scenario of replacement of mNY), while three (reader 1) or six (reader 2) patients would be additionally classified as axSpA in both scenarios (replacement of mNY and addition of MRI-SI-s). Similar results were seen for the other cut-offs (E≥3, FL≥3).
CONCLUSIONS:
Structural lesions on MRI can be used reliably either as an addition to or as a substitute for radiographs in the ASAS axSpA classification of patients in our cohort of patients with short symptom duration.
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
KEYWORDS:
Ankylosing Spondylitis; Low Back Pain; Magnetic Resonance Imaging; Spondyloarthritis
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janvier 29, 2017 | Posted by admin
Un nouvel article scientifique intitulé «Use of nonsteroidal anti-inflammatory drugs in early axial spondyloarthritis in daily practice: Data from the DESIR cohort» a été publié dans le journal Joint Bone Spine.
Molto A, Granger B, Wendling D, Dougados M, Gossec L.
OBJECTIVES:
Nonsteroidal anti-inflammatory drugs (NSAID) are the cornerstone of treatment in axial spondyloarthritis (axSpA). We [...]
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janvier 3, 2017 | Posted by admin
Un nouveau bilan du nombre de projets soumis et acceptés par le comité scientifique depuis le début de l’étude est accessible cliquer ici .
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décembre 19, 2016 | Posted by admin
Un nouvel article scientifique intitulé Reliability of mSASSS scoring in everyday practice in DESIR-cohort study centres: cross-sectional study of agreement with trained readers..» a été publié dans le journal Ann Rheum Dis.
Claudepierre P, de Hooge M, Feydy A, Reijnierse M, Saraux A, Dougados M, van der Heijde D
Ann Rheum Dis. 2016 Dec;75(12):2213-2214. doi: [...]
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novembre 19, 2016 | Posted by admin
Un nouvel article scientifique intitulé «What is the reliability of non-trained investigators in recognising structural MRI lesions of sacroiliac joints in patients with recent inflammatory back pain? Results of the DESIR cohort.» a été publié dans le journal RMD Open.
Jacquemin C, Rubio Vargas R, van den Berg R, Thévenin F, Lenczner G, Reijnierse [...]
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septembre 4, 2016 | Posted by admin
Un nouvel article scientifique intitulé « Patient-physician discordance in global assessment in early spondyloarthritis and its change over time: the DESIR cohort» a été publié dans le journal Ann Rheum Dis.
Desthieux C, Molto A, Granger B, Saraux A, Fautrel B, Gossec L.
Ann Rheum Dis. 2015 Oct 22. pii: annrheumdis-2015-208251. doi: 10.1136/annrheumdis-2015-208251.
Abstract
OBJECTIVE:
To assess patient-physician discordance in global assessment of disease activity in early [...]
Categories: Publication de travaux dans des journaux médicaux | Tags: Carole Desthieux, Coorte desir, DESIR, SPA | No Comments »
août 30, 2016 | Posted by admin
Un nouvel article scientifique intitulé « Rate and predisposing factors of sacroiliac radiographic progression after a 2 years follow-up period in recent onset spondyloarthritis.» a été publié dans le journal Arthritis Rheumatol.
Dougados M, Demattei C, van den Berg R, Hoang VV, Thevenin F, Reijnierse M, Loeuille D, Feydy A, Claudepierre P, van der Heijde D.
Arthritis [...]
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juillet 29, 2016 | Posted by admin
Un nouvel article scientifique intitulé «Responsiveness of a simple RAPID-3-like index compared to disease-specific BASDAI and ASDAS indices in patients with axial spondyloarthritis» a été publié dans le journal RDM Open.
Castrejón I, Pincus T, Wendling D, Dougados M.
OBJECTIVE:
To evaluate the responsiveness of a simple routine assessment of patient index data (RAPID3)-like index that [...]
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